Curriculum Vitae
Demographic Information
Name: Tanveer A. Khan
Address:
Cell Phone: 617-930-9480
Email: tkhan@mednet.ucla.edu
Place of Birth:
Date of Birth: December 28, 1971
Education
1994-1998 University of
M.D., June 1998
1990-1994 University of
Summa Cum Laude
A.B., Molecular and Cell Biology, June 1994
Post Graduate Training
2007-2008 University of
Division of Cardiothoracic Surgery
Transplant and Adult Cardiac Surgery Fellowship
2007
Division of Vascular Surgery
Endovascular Fellowship
2005-2007
Cardiothoracic Surgery Residency
2004-2005 Beth Israel Deaconess Medical Center
General Surgery Chief Residency
2003-2004 Beth Israel Deaconess Medical Center
General Surgery Residency
2001-2003 Beth Israel Deaconess Medical Center
Cardiothoracic Surgery Research Fellowship
1998-2001 Beth Israel Deaconess Medical Center
General Surgery Residency
Licensure
1998-2005 Massachusetts Medical License
2001-present California Medical License
Academic Appointments
2007-2008 UCLA
Clinical Instructor
2007
Postdoctoral Fellow
2003-2005 Harvard Medical School
Clinical Fellow in Surgery
2001-2003 Harvard Medical School
Research Fellow in Surgery
1998-2001 Harvard Medical School
Clinical Fellow in Surgery
1997
Teaching Assistant in Human Anatomy
Honors & Awards
2007 Robert Rosenberg Humanitarian Award
In Recognition of Dedication and Commitment to Patients
2007 The Society of Thoracic Surgeons
Resident Scholarship
Thoracic Endografting Symposium
2006 American Association for Thoracic Surgery
Resident Traveling Fellowship
1998-2005 Resident Top Score Award
American Board of Surgery In-Training Examination
2004 Resident Research Award
2002 Vivien Thomas Young Investigator Award Finalist
American Heart Association Council on Cardiothoracic and Vascular Surgery
1998 Thomas E. Carew Cardiovascular Research Award
UCSD
1998 Foundation for Surgical Education Achievement Award
UCSD
1998 Independent Study Project Poster Presentation Award
1994 Phi Beta Kappa, UC Berkeley
1993 James Hjul Honorary Academic Scholarship, UC Berkeley
1992 Nelson, A & K Honorary Academic Scholarship, UC Berkeley
Professional Society Involvement
2007-present Society of Thoracic Surgeons
Board Certification
2007 American Board of Thoracic Surgery Board Eligible
In Training Exam 99th percentile
2006 American Board of Surgery Certifying Exam Completed
2005 American Board of Surgery Qualifying Exam Completed
95th percentile
Research and Educational Grants
2007 W.L. Gore Educational Grant
Endovascular Fellowship
2007 Sorin Group Educational Grant
Endovascular Fellowship
2001-2003 NIH Individual National Research Service Award F32 HL69651
Cardiac Surgery Research Fellowship
1995 NIH Research Grant
Atherosclerosis Research Fellowship
Research Projects
2001-2005 "Molecular Mechanisms of Vasomotor Dysfunction After Cardioplegia-Cardiopulmonary Bypass."
NIH R01 HL46716
Principle Investigator: Frank Sellke
2002-2004 "Effects of Aprotinin on Reperfusion Injury and Thrombosis."
Bayer Corporation
Principle Investigator: Frank Sellke
2001-2003 “Myocardial and Systemic Vasomotor Dysfunction Due to Cardiopulmonary Bypass with Cardioplegic Arrest.”
NIH NRSA F32 HL69651
Principle Investigator: Tanveer Khan
1998 "Role of Macrosialin as a Macrophage Receptor: Cell Surface Expression and Internalization."
Independent Study Project,
Principle Investigator: Daniel Steinberg
1995 "Cell Surface Expression of Macrosialin, a Macrophage Protein which Binds Oxidized LDL."
NIH Research Fellowship,
Principle Investigator: Tanveer Khan
Invited Presentations
1) Khan TA. Poly(ADP-Ribose) Polymerase Inhibition Improves Postischemic Myocardial Function After Cardiopulmonary Bypass. Department of Surgery Capper-Hermanson Visiting Professor Research Forum,
2) Khan TA. Vasomotor Regulation During Cardiopulmonary Bypass. Surgical Grand Rounds, Department of Surgery,
3) Khan TA. Cardiopulmonary Bypass Reduces Peripheral Vasomotor Function by Mitogen Activated Protein Kinase Inhibition. Division of Cardiothoracic Surgery Visiting Professor Research Forum,
4) Khan TA. Protein Kinase Regulation of the Mesenteric Microcirculation After Cardiopulmonary Bypass. Department of Surgery Capper-Hermanson Visiting Professor Research Forum,
5) Khan TA. Mitogen-Activated Protein Kinase Inhibition and Cardioplegia-Cardiopulmonary Bypass Reduce Coronary Myogenic Tone. Division of Cardiothoracic Surgery Visiting Professor Research Forum,
6) Khan TA. What I Accomplished in Research Fellowship. Research Seminar, Department of Surgery,
7) Khan TA. Role of Heparan Sulfate in Enhanced Coronary Microvascular Relaxation Due to Chronic Myocardial Ischemia. Division of Cardiothoracic Surgery Visiting Professor Research Forum,
8) Khan TA. Diagnosis and Management of Aortic Dissection. Surgical Grand Rounds, Department of Surgery,
9) Khan TA. Aprotinin Reduces Reperfusion Injury after Regional Ischemia and Cardioplegic Arrest. Department of Surgery Clowes Visiting Professor Research Forum,
10) Khan TA. Resident Research Competition, Surgical Grand Rounds, Department of Surgery,
11) Khan TA. Aprotinin Preserves Coronary Endothelial Cellular Junctions and Reduces Myocardial Edema and Dysfunction After Regional Ischemia and Cardioplegic Arrest. Division of Cardiothoracic Surgery Visiting Professor Research Forum,
12) Khan TA. Minimally Invasive Mitral Valve Surgery: Early Outcomes and Resident Teaching. Surgical Grand Rounds, Department of Surgery,
13) Khan TA. Localized Fibrous Tumors of the Pleura. Thoracic Oncology Conferece, Division of Thoracic Surgery, UCLA
14) Khan TA. The Spectrum of N2 Non-Small Cell Lung Cancer. Thoracic Oncology Conferece, Division of Thoracic Surgery, UCLA
15) Khan TA. Mediastinoscopy. Pulmonary-Thoracic Surgery Conference,
16) Khan TA. Mitral Valve Repair. Cardiology-Cardiac Surgery Conference,
Bibliography
Original Peer-Reviewed Articles
1) Bianchi C, Wakiyama H, Faro R, Khan T, McCully J, Levitsky S, Szabo C, Sellke FW. A Novel Peroxynitrite Decomposer Catalyst (FP-15) Reduces Myocardial Infarct Size in an In Vivo Model of Acute Ischemia-Reperfusion Injury in Pigs. Ann Thorac Surg 2002 Oct; 74(4): 1201-1207.
2) Ruel M, Sellke FW, Bianchi C, Khan TA, Faro R, Zhang J-P, Cohn WE. Endogenous myocardial angiogenesis and revascularization using a gastric submucosal patch. Ann Thorac Surg 2003 May;75(5):1443-9.
3) Khan TA, Ruel M, Bianchi C, Voisine P, Komjáti K, Szabo C, Sellke FW. Poly(ADP-Ribose) Polymerase Inhibition Improves Postischemic Myocardial Function After Cardioplegia-Cardiopulmonary Bypass. J Am Coll Surg 2003 Aug;197(2):270-7.
4) Khan TA, Bianchi C, Araujo EG, Ruel M, Voisine P, Li J, Liddicoat JR, Sellke FW. Cardiopulmonary Bypass Reduces Peripheral Microvascular Function by Inhibition of Mitogen-Activated Protein Kinase Activity. Surgery 2003 Aug;134(2):247-54.
5) Khan TA, Bianchi C, Ruel M, Voisine P, Li J, Liddicoat JR, Sellke FW. Mitogen-Activated Protein Kinase Inhibition and Cardioplegia-Cardiopulmonary Bypass Reduce Coronary Myogenic Tone. Circulation 2003 Sep 9;108(10 Suppl 1):II348-53.
6) Ruel M, Wu GF, Khan TA, Bianchi C, Voisine P, Li J, Laham RJ, Li J, Sellke FW. Inhibited Angiogenic Response to Surgical FGF-2 Protein Therapy in a Swine Model of Endothelial Dysfunction. Circulation 2003 Sep 9;108(10 Suppl 1):II335-40.
7) Khan TA, Bianchi C, Araujo EG, Ruel M, Voisine P, Sellke FW. Activation of Pulmonary Mitogen-Activated Protein Kinases During Cardiopulmonary Bypass. J Surg Res 2003 Nov;115(1):56-62.
8) Ruel M, Bianchi C, Khan TA, Xu S, Liddicoat JR, Araujo E, Voisine P, Lyon H, Kohane I, Libermann TA, Sellke FW. Gene Expression Profile After Cardiopulmonary Bypass and Cardioplegic Arrest. J Thorac Cardiovasc Surg 2003 Nov;126(5):1521-30.
9) Voisine P, Bianchi C, Ruel M, Malik T, Rosinberg A, Khan TA, Xu S, Sandmeyer J, Laham RJ, Sellke FW. Inhibition of the Cardiac Angiogenic Response to Exogenous Vascular Endothelial Growth Factor Therapy in a Porcine Model of Endothelial Dysfunction. Surgery 2004 Aug;136(2):407-15.
10) Voisine P, Ruel M, Khan TA, Bianchi C, Xu S, Kohane I, Libermann TA, Otu H, Saltiel AR, Sellke FW. Differences in Gene Expression Profiles of Diabetic and Non-diabetic Patients Undergoing Cardiopulmonary Bypass and Cardioplegic Arrest. Circulation 2004 Sep 14;110(11 Suppl 1):II280-II286.
11) Khan TA, Bianchi C, Feng J, Voisine P, Ruel M, Li J, Hart M, Takahashi M, Sellke FW. Aprotinin Reduces Reperfusion Injury after Regional Ischemia and Cardioplegic Arrest. J Thorac Cardiovasc Surg 2004 Oct;128(4):602-8.
12) Khan TA, Bianchi C, Voisine P, Feng J, Sandmeyer J, Sellke FW. Aprotinin Inhibits Protease-Dependent Platelet Aggregation and Thrombosis. Annals of Thoracic Surgery 2005 May;79(5):1545-50.
13) Voisine P, Bianchi C, Khan TA, Ruel M, Xu S, Feng J, Li J, Malik T, Sellke FW. Normalization of Coronary Microvascular Reactivity and Improvement in Myocardial Perfusion by Surgical VEGF Therapy Combined With Oral Supplementation of L-Arginine in a Porcine Model of Endothelial Dysfunction. J Thorac Cardiovasc Surg. 2005 Jun;129(6):1414-20.
14) Voisine P, Li J, Bianchi C, Khan TA, Ruel M, Xu S, Feng J, Rosinberg A, Malik T, Nakai Y, Sellke FW. L-Arginine Supplementation Improves the Inhibited Angiogenic Response to FGF in a Porcine Model of Myocardial Ischemia with Endothelial Dysfunction. Circulation. 2005 Aug 30;112(9 Suppl):I202-7.
15) Khan T, Voisine P, Bianchi C, Rosinberg A, Bianchi C, Feng J, Malik T, Sellke FW. Aprotinin Preserves Coronary Endothelial Cellular Junctions and Reduces Myocardial Edema After Regional Ischemia and Cardioplegic Arrest. Circulation. 2005 Aug 30;112(9 Suppl):I196-201.
16) Khan T, Bianchi C, Ruel M, Feng J, Sellke F. Differential effects on the mesenteric microcirculatory response to vasopressin and phenylephrine after cardiopulmonary bypass. J Thorac Cardiovasc Surg 2007 Mar;133(3):682-8.
Invited Reviews
1) Khan TA, Sellke FW, Laham RJ. Therapeutic Angiogenesis for Coronary Artery Disease. Curr Treat Options Cardiovasc Med. 2002 Feb;4(1):65-74.
2) Khan TA, Sellke FW, Laham RJ. Protein-Based Therapeutic Angiogenesis. Expert Opin Pharmacother. 2003 Feb;4(2):219-26.
3) Khan TA, Sellke FW, Laham RJ. Gene Therapy Progress and Prospects:
Therapeutic Angiogenesis for Limb and Myocardial Ischemia. Gene Ther 2003 Feb;10(4):285-91.
4) Khan TA, Bianchi C, Ruel M, Voisine P, Sellke FW. Mitogen-Activated Protein Kinase Pathways and Cardiac Surgery. J Thorac Cardiovasc Surg 2004 Mar;127(3):806-11.
5) Rosinberg A, Khan TA, Sellke FW, Laham RJ. Therapeutic Angiogenesis for Myocardial Ischemia. Exp Rev Cardiovascular Therapy 2004 Mar;2(2):271-83.
6) Ruel M, Khan TA, Voisine P, Bianchi C, Sellke F. Vasomotor Dysfunction after Cardiac Surgery. Eur J Cardiothorac Surg 2004 Nov;26(5):1002-14.
Book Chapters
1) Khan TA, Voisine P, Sellke FW. Diabetes Mellitus and Cardiac Surgery. In:
Nonprint Material
1) Khan TA, Sellke FW, Laham RJ. Gene Therapy Progress and Prospects: Therapeutic Angiogenesis for Limb and Myocardial Ischemia. Nature View, www.nature.com; Feb 24, 2003.
Abstracts
1) Khan T, Steinberg D. Cell Surface Expression of Macrosialin, a Macrophage Protein which Binds Oxidized LDL.
2) Khan T, Ramprasad M, Steinberg D. Role of Macrosialin as a Macrophage Receptor: Cell Surface Expression and Internalization.
3) Khan TA, Ruel M, Bianchi C, Csaba C, Sellke FW. Poly ADP-Ribose Synthetase Inhibition Improves Postischemic Myocardial Function After Cardiopulmonary Bypass. 51st Annual Meeting of the Scandinavian Association for Thoracic Surgery.
4) Khan T, Bianchi C, Ruel M, Sellke F. Effects of Cardiopulmonary Bypass on Mitogen-Activated Protein Kinase Activation and Peripheral Microvascular Contractile Responses in Humans. 51st Annual Meeting of the Scandinavian Association for Thoracic Surgery.
5) Ruel M, Khan TA, Bianchi C, Liddicoat JR, Cohn WE, Liberman T, Kohane I, Sellke FW. Genomic Profile of the Response to Cardiopulmonary Bypass in Humans. 51st Annual Meeting of the Scandinavian Association for Thoracic Surgery.
6) Khan TA, Bianchi C, Ruel M, Li J, Cohn WE, Liddicoat JR, Sellke FW. Mitogen-Activated Protein Kinases and Vasomotor Dysfunction After Cardiopulmonary Bypass. American Physiological Society Myogenic Centennial Conference.
7) Khan TA, Ruel M, Bianchi C, Szabo C, Sellke FW. Poly ADP-Ribose Synthetase Inhibition Improves Postischemic Myocardial Function After Cardiopulmonary Bypass. 88th Annual Clinical Congress of the
8) Khan TA, Bianchi C, Ruel M, Voisine P, Araujo E, Li J, Liddicoat JR, Sellke FW. Mitogen-Activated Protein Kinase Inhibition and Cardiopulmonary Bypass Reduce Coronary Myogenic Tone.
9) Khan T, Ruel M, Bianchi C, Szabo C, Sellke FW. Inhibition of Poly ADP-Ribose Synthetase Improves Postischemic Myocardial Function After Cardiopulmonary Bypass.
Canadian Cardiovascular Congress 2002 of the Canadian Cardiovascular Society.
10) Khan T, Bianchi C, Ruel M, Sellke F. Mitogen-Activated Protein Kinase Activation and Vasomotor Dysfunction After Cardiopulmonary Bypass. Canadian Cardiovascular Congress 2002 of the Canadian Cardiovascular Society.
11) Ruel M, Bianchi C, Khan TA, Xu S, Liddicoat JR, Cohn WE, Liberman T, Lyon H, Kohane I, Sellke FW. Genomic Expression Profile of the Clinical Response to Cardiopulmonary Bypass. Canadian Cardiovascular Congress 2002 of the Canadian Cardiovascular Society.
12) Ruel M, Wu GF, Khan TA, Bianchi C, Cohn WE, Laham RJ, Li J, Sellke FW. Surgical Angiogenesis with FGF-2 is Impaired by Endothelial Dysfunction. Canadian Cardiovascular Congress 2002 of the Canadian Cardiovascular Society.
13) Khan TA, Bianchi C, Faro R, Ruel M, Sellke FW. Activation of Pulmonary Mitogen-Activated Protein Kinases During Cardiopulmonary Bypass. Annual Meeting of the Association of Academic Surgery.
14) Khan TA, Bianchi C, Ruel M, Liddicoat JR, Li J, Sellke FW. Mitogen-Activated Protein Kinase Inhibition and Cardiopulmonary Bypass Reduce Coronary Myogenic Tone. Scientific Sessions 2002 of the American Heart Association.
15) Ruel M, Wu GF, Khan TA, Bianchi C, Cohn WE, Li J, Laham RJ, Sellke FW. Inhibited Angiogenic Response to Surgical FGF-2 Protein Therapy in a Swine Model of Endothelial Dysfunction. Scientific Sessions 2002 of the American Heart Association.
16) Ruel M, Bianchi C, Khan TA, Xu S, Cohn WE, Liddicoat JR, Lyon H, Liberman T, Kohane I, Sellke FW. Genomic Expression Profile of the Clinical Response to Cardiopulmonary Bypass. Scientific Sessions 2002 of the American Heart Association.
17) Khan TA, Bianchi C, Araujo EG, Ruel M, Voisine P, Li J, Liddicoat JR, Sellke FW. Cardiopulmonary Bypass Reduces Peripheral Microvascular Function by Inhibition of Mitogen-Activated Protein Kinase Activity. Society of University Surgeons Annual Meeting.
18) Khan TA, Ruel M, Bianchi C, Voisine P, Li J, Xu S, Laham RJ, Sellke FW. Chronic Myocardial Ischemia Increases Syndecan-4 Expression and Alters Coronary Microvascular Function. Society of University Surgeons Annual Meeting.
19) Khan TA, Ruel M, Bianchi C, Voisine P, Sellke FW. Protein Kinase Regulation of the Mesenteric Microcirculation After Cardiopulmonary Bypass. 89th Annual Clinical Congress of the
20) Voisine P, Ruel M, Khan TA, Bianchi C, Xu S, Kohane I, Libermann TA, Sellke FW. Gene Expression Profile in Diabetic Patients After Cardiopulmonary Bypass and Cardioplegic Arrest. Canadian Cardiovascular Congress 2003 of the Canadian Cardiovascular Society.
21) Voisine P, Ruel M, Bianchi C, Khan TA, Xu S, Feng J, Laham RJ, Sellke FW. Hypercholesterolemia-Induced Resistance to Exogenous FGF-2 Effects on Endothelial Function in a Swine Model of Chronic Myocardial Ischemia. Canadian Cardiovascular Congress 2003 of the Canadian Cardiovascular Society.
22) Voisine P, Yadlapalli N, Khan TA, Laham RJ, Roy-Chaudhury P, Burnett SK, Bianchi C, Sellke FW, Sukhatme VP. Expression of a Platelet-Derived Growth Factor (PDGF)-Signaling Pathway in a Porcine Model of Arterio-Venous (AV) Graft Stenosis. Canadian Cardiovascular Congress 2003 of the Canadian Cardiovascular Society.
23) Khan TA, Voisine P, Ruel M, Bianchi C, Feng J, Xu S, Li J, Sellke FW. Role of Heparan Sulfate in Enhanced Coronary Microvascular Relaxation Due to Chronic Myocardial Ischemia. Presented at the Scientific Sessions 2003 of the American Heart Association.
24) Khan TA, Bianchi C, Voisine P, Ruel M, Feng J, Hart M, Takahashi M, Stahl G, Sellke FW. Aprotinin Reduces Reperfusion Injury After Regional Ischemia and Cardioplegic Arrest. Presented at the Scientific Sessions 2003 of the American Heart Association.
25) Voisine P, Ruel M, Khan TA, Bianchi C, Xu S, Kohane I, Libermann TA, Sellke FW. Differences in Gene Expression Profiles of Diabetic and Non-diabetic Patients Undergoing Cardiopulmonary Bypass and Cardioplegic Arrest. Scientific Sessions 2003 of the American Heart Association.
26) Voisine P, Ruel M, Bianchi C, Khan TA, Xu S, Feng J, Laham RJ, Sellke FW. Chronic Hypercholesterolemia Induces Resistance to the Exogenous Effects of FGF-2 on Endothelial Function in a Swine Model of Chronic Myocardial Ischemia. Scientific Sessions 2003 of the American Heart Association.
27) Voisine P, Ruel M, Bianchi C, Khan TA, Xu S, Feng J, Li J, Laham RJ, Malik T, Sellke FW. Inhibition of the Cardiac Angiogenic Response to Exogenous Vascular Endothelial Growth Factor Therapy in a Porcine Model of Endothelial Dysfunction. Society of University Surgeons Annual Meeting.
28) Voisine P, Yadlapalli N, Khan TA, Laham RJ, Roy-Chaudhury P, Kelly BS, Bianchi C, Sellke FW, Sukhatme VP. Expression of a Platelet-Derived Growth Factor (PDGF)-Signaling Pathway in a Porcine Model of Arterio-Venous (AV) Graft Stenosis. Society of University Surgeons Annual Meeting.
29) Voisine P, Bianchi C, Khan TA, Ruel M, Xu S, Feng J, Li J, Malik T, Sellke FW. Normalization of Coronary Microvascular Reactivity and Improvement in Myocardial Perfusion by Surgical VEGF Therapy Combined With Oral Supplementation of L-Arginine in a Porcine Model of Endothelial Dysfunction. American Association for Thoracic Surgery Annual Meeting.
30) Khan T, Voisine P, Bianchi C, Rosinberg A, Bianchi C, Feng J, Malik T, Sellke FW. Aprotinin Preserves Coronary Endothelial Cellular Junctions and Reduces Myocardial Edema After Regional Ischemia and Cardioplegic Arrest. Scientific Sessions 2004 of the American Heart Association.
31) Voisine P, Li J, Bianchi C, Khan TA, Ruel M, Xu S, Feng J, Rosinberg A, Malik T, Nakai Y, Sellke FW. L-Arginine Supplementation Improves the Inhibited Angiogenic Response to FGF in a Porcine Model of Myocardial Ischemia with Endothelial Dysfunction. Scientific Sessions 2004 of the American Heart Association.
32) Ramlawi B, Khan TA, Ruel M, Voisine P, Bianchi C, Liddicoat J, Boodhwani M, Sellke F. Variations in Gene Expression Profiles Following Cardiac Surgery in Diabetic Patients and their Clinical Correlation. 91st Annual Clinical Congress of the
33) Marelli D, Kobashigawa JA, Moriguchi JD, Shuvayev I, Wong SY, Khan T, Patel JK, Beygui R, Esmailian F, Laks H, Plunkett MD, and Ardehali A. ECMO to salvage severe cardiogenic shock in advanced heart failure and transplantation. The International Society for Heart and Lung Transplantation 28th Annual Meeting and Scientific Sessions. Boston, MA. April 9-12, 2008.
Training Courses
1) Novotherapies: New and Emerging Technologies for the Cardiac Surgeon
Arizona Heart Institute, November 10-15, 2005
Training in endovascular thoracic stent grafting
2) Edwards CO2 Laser Revascularization
Training in transmyocardial laser revascularization (TMR)
3) Edwards Basic Endovascular Skills Training
Training in guidewire, catheter, and fluoroscopic imaging skills
4) The Society of Thoracic Surgeons Thoracic Endografting Symposium
Didactic and hands-on training in thoracic endografting